12 clinics in San Francisco, CA
4.8/5 Google rating

Weight Loss Shots in San Francisco, California

In San Francisco, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a California-licensed clinician, who confirms your eligibility and sets your weekly dose.

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Weight loss shots in San Francisco, CA
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Where to get weight loss shots in San Francisco

In San Francisco, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a California-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near San Francisco

The clinics listed for San Francisco offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to San Francisco within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in San Francisco

In San Francisco, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your California plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in San Francisco

Three simple steps, online or at a local clinic

1
Online eligibility check

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed California provider confirms if a GLP-1 is right for you.

2
Clinic or online provider

Get your prescription

Choose a local San Francisco clinic for in-person care, or an online provider who ships medication to your door.

3
Start weekly treatment

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Am I eligible for a GLP-1 in San Francisco?

Most providers require a BMI of 30 or higher, or 27+ with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. Check your BMI in seconds:

  • BMI 30+ — generally eligible
  • BMI 27–29 with a comorbidity — often eligible
  • A licensed California provider confirms in minutes
Quick BMI check

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to San Francisco patients

ShotMoleculeApproved forFrequencyTypical price
Ozempic Semaglutide Type 2 diabetes (off-label weight loss) Once weekly $950–$1,350/mo
Wegovy Semaglutide Chronic weight management Once weekly $1,300–$1,400/mo
Mounjaro Tirzepatide Type 2 diabetes (off-label weight loss) Once weekly $1,000–$1,200/mo
Zepbound Tirzepatide Chronic weight management Once weekly $1,000–$1,060/mo
Compounded Semaglutide / Tirzepatide Cash-pay telehealth option Once weekly $199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in San Francisco

Compare by speed, price and how you prefer to be seen

Local clinics & med spas

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care
See clinics below
Retail pharmacy + insurance

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage
Learn more

Weight loss clinics in San Francisco, CA

12 clinics offering GLP-1 treatment near San Francisco, ranked by Google rating

#1
Vital Weight Loss MD

Vital Weight Loss MD

Weight loss service Today: 9 AM–5 PM
4200 18th St Ste 103 A, San Francisco, CA 94114
(415) 915-5100
#2
Orthopedic Physical Therapy And Wellness Inc.

Orthopedic Physical Therapy And Wellness Inc.

4.3 Weight loss service Today: 8 AM–5 PM
20 Sycamore St, San Francisco, CA 94110
(415) 480-8011
“Theyre very kind and close to bart” — Leah Mahler
#3
UCSF Bariatric Surgery Center

UCSF Bariatric Surgery Center

5.0 (2 reviews) Weight loss service Today: 8 AM–5 PM
400 Parnassus Ave Second Floor, San Francisco, CA 94143
(415) 353-2804
“They saved my life! I couldn't hardly walk. I was not a part of family functions because I would always find a corner to hide in. I was depressed. Now I walk, …” — Brenda Hawkins
#4

Pacific Laparoscopy

5.0 Walk-in clinic
2250 Hayes St #300, San Francisco, CA 94117
(415) 668-3200
“I was 5 foot 4 and weighed 348 pounds at 51. Fortunately, my older brother had gone to Dr. Rabkin. I am 72 years, old take no medications, and weigh 135 poi…” — julia fritz
#5
UCSF Weight Management Program

UCSF Weight Management Program

Medical clinic Today: 8 AM–5 PM
1600 Divisadero St #500, San Francisco, CA 94143
(415) 353-7999
#6
St Mary's

St Mary's

Weight loss service
450 Stanyan St, San Francisco, CA 94117
(855) 202-3459
#7
Weight Loss Nutritionist San Francisco

Weight Loss Nutritionist San Francisco

5.0 Weight loss service Today: 8:30 AM–6 PM
870 Market St, San Francisco, CA 94102
(415) 871-4388
“I have been working with Rania from Essential Nutrition for about ten weeks now, and hands down, it has been one of the best things I ever did for myself. For …” — Irena Stošić
#8
Coach Patrick Liu | Personal Training & Weight Loss San Francisco

Coach Patrick Liu | Personal Training & Weight Loss San Francisco

5.0 Weight loss service Today: 7 AM–6 PM
1428 Irving St, San Francisco, CA 94122
(415) 417-1966
“Great supporting team, who are very helpful with any questions or concerns you have about the program or anything thing that can support you in your fitness/he…” — Karissa Rios
#9
JumpstartMD

JumpstartMD

4.3 (11 reviews) Weight loss service Today: 7 AM–1 PM
390 Laurel St Ste 207, San Francisco, CA 94118
(415) 936-1105
“The professionals at Jumpstart are friendly, knowledgeable, and efficient. I particularly liked how they tailored their thoughtful approach to meet my specific…” — Oscar Vasquez
#10
PlushCare HQ

PlushCare HQ

4.4 Weight loss service
2261 Market St Ste 22930, San Francisco, CA 94114
(800) 221-5140
“I would give Plush Care zero stars if I could. They act as a virtual PCP (Primary Care Provider) in place of a traditional, in-person general practitioner. Bec…” — Dani S
#11
Barbara Berkeley, DC

Barbara Berkeley, DC

5.0 Chiropractor Today: 10 AM–7 PM
3340 A 18th St, San Francisco, CA 94110
“I won't hesitate to send all other sufferers to Dr Berkeley next time.<br><br>Not only did she miraculously fix a very stubborn months-old S.I.<br>lower lumbar…” — Elgy Gillespie
#12
Homemade Method

Homemade Method

4.8 (89 reviews) Weight loss service Today: 9 AM–9 PM
84A Richland Ave, San Francisco, CA 94110
(888) 292-4624
“Tons of great recipes and quick responses to questions. Lots of online support and training.” — Debbie Frick

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to San Francisco in a few days.

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What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most San Francisco patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in San Francisco

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in San Francisco, California

Brand-name shots run about $1,000–$1,400/month without insurance in San Francisco. Compounded semaglutide or tirzepatide via telehealth starts around $199/month all-inclusive. With California insurance coverage, copays can be as low as $25–$50.

Not much. The shots use a short, thin needle (4–5 mm) injected just under the skin, and most patients describe it as a quick pinch. Your San Francisco provider or clinic will show you how to self-inject, rotating between the abdomen, thigh and upper arm.

Compounded semaglutide and tirzepatide are made by 503A/503B pharmacies regulated by state boards and the FDA, with purity independently tested. They contain the same active ingredient as the brand-name shots. Your San Francisco provider monitors your progress and adjusts your dose.

GLP-1 medications are given as a once-weekly subcutaneous injection with a small, thin needle — either a prefilled pen or a vial and syringe. They slow gastric emptying, reduce appetite and signal fullness to the brain. Most San Francisco patients self-inject at home after a quick demonstration; all supplies are included.

No. San Francisco telehealth providers offer cash-pay compounded options with a free online consultation, and HSA/FSA cards are accepted. Insurance is applied when available to further reduce your cost.

Both are tirzepatide from Eli Lilly. Mounjaro is approved for type 2 diabetes, Zepbound for chronic weight management. The molecule and weekly dosing are identical — only the indication differs.

GLP-1 weight loss explained

Weight loss clinics near San Francisco

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Weight Loss Shots and GLP-1 clinics across California

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Ready to start GLP-1 treatment in San Francisco?

Compare local clinics above, or get a prescription online from a licensed California provider and have it delivered.

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Find Weight Loss Shots