12 clinics in Rochester, MN

4.5/5 Google rating

Weight Loss Shots in Rochester, Minnesota

In Rochester, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Minnesota-licensed clinician, who confirms your eligibility and sets your weekly dose.

Find Weight Loss Shots

Local clinics + online Licensed providers Delivery in 2–3 days From $199/mo

Where to get weight loss shots in Rochester

Semaglutide and tirzepatide shots near Rochester

The clinics listed for Rochester offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Rochester within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Rochester

In Rochester, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your Minnesota plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Rochester

Three simple steps, online or at a local clinic

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed Minnesota provider confirms if a GLP-1 is right for you.

Get your prescription

Choose a local Rochester clinic for in-person care, or an online provider who ships medication to your door.

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Rochester patients

Shot	Molecule	Approved for	Frequency	Typical price
Ozempic	Semaglutide	Type 2 diabetes (off-label weight loss)	Once weekly	$950–$1,350/mo
Wegovy	Semaglutide	Chronic weight management	Once weekly	$1,300–$1,400/mo
Mounjaro	Tirzepatide	Type 2 diabetes (off-label weight loss)	Once weekly	$1,000–$1,200/mo
Zepbound	Tirzepatide	Chronic weight management	Once weekly	$1,000–$1,060/mo
Compounded	Semaglutide / Tirzepatide	Cash-pay telehealth option	Once weekly	$199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Rochester

Compare by speed, price and how you prefer to be seen

Telehealth delivery

From $199/mo (compounded)

Online consultation with a licensed provider, medication shipped to your door. Fastest cash-pay route, no insurance needed.

Best for speed & convenience

Find Weight Loss Shots

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care

See clinics below

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage

Learn more

Weight loss clinics in Rochester, MN

12 clinics offering GLP-1 treatment near Rochester, ranked by Google rating

Enara Health at Olmsted Medical Center

Weight loss service Today: Open 24 hours

210 9th St SE, Rochester, MN 55904

Olmsted Medical Center - Weight Loss Surgery

Medical clinic

1650 4th St SE, Rochester, MN 55904

(507) 529-6733

Rejuvenate Spa at Mayo Clinic

4.8 Medical spa Today: 8 AM–5:30 PM

565 1st St SW Floor 5, Rochester, MN 55902

(507) 293-2966

“Amazing services! Massage therapists and acupuncture therapists are great” — S S

Mayo Clinic Bariatric Surgery Program

Bariatric surgeon Today: 7 AM–6 PM

200 1st St SW, Rochester, MN 55905

(507) 792-9948

Lite Medical Clinic PLLC - Rochester

5.0 Weight loss service Today: 7 AM–10 PM

3269 19th St NW Ste 140, Rochester, MN 55901

(952) 260-9520

“Great experience!” — Alicia Schultz

Rochester Weight Loss

3.4 (5 reviews) Weight loss service Today: 9 AM–5 PM

2774 Commerce Dr NW Ste C, Rochester, MN 55901

(507) 460-1150

“Program requires coaching calls and they were not helpful. Coach forgot about my appointments frequently which was annoying.” — Tasha Graham

Driftless Hydration and Wellness

4.9 Weight loss service

17 12th St NE, Rochester, MN 55906

(507) 258-3052

“Everything was perfect! Welcoming, friendly and knew exactly what I needed. I will forever be a repeat customer!!” — Heather Millard

Essence Skin Clinic & Med Spa

4.9 Medical spa Today: 9 AM–5 PM

1640 W Center St, Rochester, MN 55902

(507) 285-5505

“Kim took time to get my lash refill looking good and educated me on how to continue with the best results!!” — Dawn Leppert

Visionworks

3.1 Optometrist Today: 10 AM–8 PM

640 Apache Mall, Rochester, MN 55902

(507) 252-1540

“I had Destine working with me....very knowledgeable, gave honest opinion, and helped get the best price with coupons etc for 4 pairs of glasses” — Linda Stenzel

#10

The Fit Loon

4.6 Weight loss service Today: 6 AM–4 PM

210 N Broadway Ave, Rochester, MN 55906

(507) 206-3131

“Healthy alternatives when you're on the run. I love their shakes and teas during the work day. Their teas have caffeine but don't make you crash a coupl…” — Kati Sletten

#11

Barham K. Abu Dayyeh, MD, MPH

5.0 Endoscopist

200 1st St SW, Rochester, MN 55905

(507) 284-2511

“Clearly explained procedure Very respectful and cordial Came back quickly at end of procedure and explained results Patients answered all questions<br…” — Judith Freiburger

#12

Dan Abraham Healthy Living Center

4.8 Medical clinic Today: Open 24 hours

565 1st St SW, Rochester, MN 55902

(507) 266-4688

“Awesome place!” — Azeret Rios

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Rochester in a few days.

Find Weight Loss Shots

What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Rochester patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Rochester

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Rochester, Minnesota

Most people notice reduced appetite within the first week or two, with meaningful weight loss over months. Trials showed ~5–10% loss by three months. Providers in Rochester start you at a low dose and increase gradually, so results build steadily rather than overnight.

You have three routes in Rochester: a licensed telehealth provider who ships medication to your door, a local weight-loss clinic or med spa for in-person care, or a retail pharmacy with a prescription (cheapest if insurance covers it). The clinics listed on this page are real, ranked by Google rating, with reviews and hours.

Clinical trials show tirzepatide (Mounjaro/Zepbound) produces greater average weight loss (up to ~22.5% of body weight) than semaglutide (Ozempic/Wegovy, ~15–17%). Tirzepatide activates two receptors (GLP-1 and GIP) versus one for semaglutide. Both are highly effective; your Rochester provider helps choose based on your history and goals.

In clinical trials, semaglutide patients lost about 15% of body weight and tirzepatide patients up to 22.5% over roughly 68–72 weeks on the highest dose. For a 200-pound person that is roughly 30–45 pounds. Results in Rochester vary with diet, activity and starting weight.

Compounded GLP-1s are prepared by 503A/503B pharmacies regulated by state boards and the FDA, with purity independently tested. They contain the same active ingredient as the brand-name drugs. Your Rochester provider monitors your progress and adjusts your protocol as needed.

Coverage varies widely by plan in Minnesota. Many commercial plans cover Mounjaro for diabetes and Wegovy/Zepbound for weight management with prior authorization. Medicare Part D may cover diabetes indications but generally not weight-loss use. A Rochester provider can verify benefits and file prior authorization.

Weight Loss Shots in Rochester, Minnesota

Where to get weight loss shots in Rochester

Semaglutide and tirzepatide shots near Rochester

What weight loss shots cost in Rochester