Weight Loss Shots in St. Louis, Missouri

Where to get weight loss shots in St. Louis

In St. Louis, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Missouri-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near St. Louis

The clinics listed for St. Louis offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to St. Louis within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in St. Louis

In St. Louis, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your Missouri plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to St. Louis patients

Shot	Molecule	Approved for	Frequency	Typical price
Ozempic	Semaglutide	Type 2 diabetes (off-label weight loss)	Once weekly	$950–$1,350/mo
Wegovy	Semaglutide	Chronic weight management	Once weekly	$1,300–$1,400/mo
Mounjaro	Tirzepatide	Type 2 diabetes (off-label weight loss)	Once weekly	$1,000–$1,200/mo
Zepbound	Tirzepatide	Chronic weight management	Once weekly	$1,000–$1,060/mo
Compounded	Semaglutide / Tirzepatide	Cash-pay telehealth option	Once weekly	$199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in St. Louis

Compare by speed, price and how you prefer to be seen

Telehealth delivery

From $199/mo (compounded)

Online consultation with a licensed provider, medication shipped to your door. Fastest cash-pay route, no insurance needed.

Best for speed & convenience

Find Weight Loss Shots

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care

See clinics below

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage

Learn more

Weight loss clinics in St. Louis, MO

12 clinics offering GLP-1 treatment near St. Louis, ranked by Google rating

Renew Vitality Testosterone Clinic of St Louis

4.9 (17 reviews) Weight loss service Today: 8 AM–7 PM

10 S Euclid Ave Unit G, St. Louis, MO 63108

(314) 798-7720

“Couldn’t be happier with the support I get from Coleman and the doctor very quick response time with any questions I have” — Charly McCoy

MOOV Health & Wellness

5.0 Wellness center Today: 1–7 PM

1530 S Kingshighway Blvd #105, St. Louis, MO 63110

(314) 252-0324

“I feel fully supported by Dr. Priyanka and her staff. She took the time to cover my labwork in depth and explained what I need to do to be healthier. I look fo…” — Jackie Inman

St. Louis Weight Loss Clinic

Health counselor Today: Open 24 hours

20 N 8th St, St. Louis, MO 63101

Holistik Wellness Center

4.9 Wellness center Today: 9 AM–5 PM

4255 Laclede Ave Ste A, St. Louis, MO 63108

(314) 735-5156

“Very Professional, Informative and welcoming as she helped me navigate my wellness journey!!! What a GEM!!” — Kenneth Daniels

STL Weight Loss & Med Spa

4.8 (100 reviews) Weight loss service Today: 12–7 PM

8079 Manchester Rd, Brentwood, MO 63144

(314) 280-5764

“Love the experience & staff! Thank You” — Megan Andersen

Knights of Columbus Developmental Center

2.9 Medical clinic Today: 8 AM–4 PM

3800 Park Ave Second Floor, St. Louis, MO 63110

(314) 577-5609

“Missed diagnosed my son and stated he was too young to be diagnosed with autism. I had him retested from a different facility and they immediately diagnosed hi…” — Amy Staryak

Aesthetic Medical Associates LLC

4.0 Medical clinic Today: 7:45 AM–3:45 PM

3920 Lindell Blvd #105, St. Louis, MO 63108

(314) 652-8923

“I saw Dr. Hollie this last Wednesday. She listens and cares. She is a very professional and knowledgeable doctor. My wife recommended her and has been seei…” — Robbie Donaldson

Big Fitness Personal Training

4.7 Weight loss service Today: 5 AM–8 PM

1904 Washington Ave, St. Louis, MO 63103

(314) 384-8473

“Don’t answer phone, tried walking in got turn around to call the same number that don’t answer” — Dell Google

Monitored Life LLC

5.0 Drug testing service Today: 9 AM–5 PM

12 N Sarah St, St. Louis, MO 63108

“Excellent service Offered<br>Great Customer Service<br>Warm atmosphere<br>Would absolutely recommend this establishment for all your testing needs.” — Cydnae LaRue

#10

Saint Fitness Collective

5.0 Weight loss service Today: 6 AM–7 PM

3411 Gratiot St, St. Louis, MO 63103

(636) 384-0444

“Great experience and environment. Worth the investment both in yourself and the community.” — Nicholas LaConte

#11

The L.A.B. Gym

4.8 Weight loss service Today: 9 AM–7 PM

3738 Chouteau Ave, St. Louis, MO 63110

(314) 671-0542

“I've been working out with Coach Tami since November 2025 and am lifting weights, utilizing machines, losing significant pounds, gaining strength and confidenc…” — Betsy Primo

#12

Love In Action Health & Wellness

4.9 Weight loss service Today: 9:30 AM–4:30 PM

2350 S 7th St, St. Louis, MO 63104

(314) 809-7776

“Awesome Experience!!!<br>Imani’s customer service is outstanding. The red light therapy sessions have benefitted me greatly. Thank you!!” — India CornellMoore

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to St. Louis in a few days.

Find Weight Loss Shots

What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most St. Louis patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in St. Louis

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in St. Louis, Missouri

You can get weight loss shots in St. Louis at the local medical weight-loss clinics ranked on this page, or online through a licensed telehealth provider that ships semaglutide or tirzepatide to your home. Both require a prescription from a Missouri-licensed provider.

You have three routes in St. Louis: a licensed telehealth provider who ships medication to your door, a local weight-loss clinic or med spa for in-person care, or a retail pharmacy with a prescription (cheapest if insurance covers it). The clinics listed on this page are real, ranked by Google rating, with reviews and hours.

Clinical trials show tirzepatide (Mounjaro/Zepbound) produces greater average weight loss (up to ~22.5% of body weight) than semaglutide (Ozempic/Wegovy, ~15–17%). Tirzepatide activates two receptors (GLP-1 and GIP) versus one for semaglutide. Both are highly effective; your St. Louis provider helps choose based on your history and goals.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks as the dose increases. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns. Your St. Louis provider starts you low and monitors progress.

Both are semaglutide from Novo Nordisk. Ozempic is FDA-approved for type 2 diabetes (often used off-label for weight loss), while Wegovy is approved specifically for chronic weight management at a higher dose. Same molecule, different indication and dosing.

Both are tirzepatide from Eli Lilly. Mounjaro is approved for type 2 diabetes, Zepbound for chronic weight management. The molecule and weekly dosing are identical — only the indication differs.

Weight Loss Shots in St. Louis, Missouri

Where to get weight loss shots in St. Louis

Semaglutide and tirzepatide shots near St. Louis

What weight loss shots cost in St. Louis

How to get weight loss shots in St. Louis

Check your eligibility

Get your prescription

Start weekly treatment

Am I eligible for a GLP-1 in St. Louis?

Semaglutide vs. tirzepatide & the GLP-1 options