12 clinics in Cleveland, OH
4.6/5 Google rating

Weight Loss Shots in Cleveland, Ohio

In Cleveland, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Ohio-licensed clinician, who confirms your eligibility and sets your weekly dose.

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Weight loss shots in Cleveland, OH
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Where to get weight loss shots in Cleveland

In Cleveland, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Ohio-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near Cleveland

The clinics listed for Cleveland offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Cleveland within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Cleveland

In Cleveland, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your Ohio plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Cleveland

Three simple steps, online or at a local clinic

1
Online eligibility check

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed Ohio provider confirms if a GLP-1 is right for you.

2
Clinic or online provider

Get your prescription

Choose a local Cleveland clinic for in-person care, or an online provider who ships medication to your door.

3
Start weekly treatment

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Am I eligible for a GLP-1 in Cleveland?

Most providers require a BMI of 30 or higher, or 27+ with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. Check your BMI in seconds:

  • BMI 30+ — generally eligible
  • BMI 27–29 with a comorbidity — often eligible
  • A licensed Ohio provider confirms in minutes
Quick BMI check

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Cleveland patients

ShotMoleculeApproved forFrequencyTypical price
Ozempic Semaglutide Type 2 diabetes (off-label weight loss) Once weekly $950–$1,350/mo
Wegovy Semaglutide Chronic weight management Once weekly $1,300–$1,400/mo
Mounjaro Tirzepatide Type 2 diabetes (off-label weight loss) Once weekly $1,000–$1,200/mo
Zepbound Tirzepatide Chronic weight management Once weekly $1,000–$1,060/mo
Compounded Semaglutide / Tirzepatide Cash-pay telehealth option Once weekly $199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Cleveland

Compare by speed, price and how you prefer to be seen

Local clinics & med spas

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care
See clinics below
Retail pharmacy + insurance

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage
Learn more

Weight loss clinics in Cleveland, OH

12 clinics offering GLP-1 treatment near Cleveland, ranked by Google rating

#1
Yevo Semaglutide & Weight Loss of Cleveland

Yevo Semaglutide & Weight Loss of Cleveland

Weight loss service Today: Open 24 hours
5217 Franklin Blvd, Cleveland, OH 44102
(216) 483-0679
#2
Euro Look Med Spa

Euro Look Med Spa

5.0 Weight loss service Today: 10 AM–6:30 PM
2678 W 14th St, Cleveland, OH 44113
(440) 444-9882
“Marta is highly experienced and thorough in her knowledge of all the things! I’ve gone for several different services, and her expertise and guidance has been …” — Becki Silverstein
#3
MetroHealth

MetroHealth

Weight loss service Today: 8 AM–5 PM
2500 Metrohealth Dr, Cleveland, OH 44109
(216) 778-7433
#4
Azurewellness

Azurewellness

5.0 Beauty salon Today: 11 AM–7 PM
2037 W 25th St, Cleveland, OH 44113
(440) 999-3623
“Azure Wellness provided exceptional care for my grandmother, and I couldn't be more grateful. From the initial consultation, their team was kind, patient, and …” — Thias Fritz
#5
MetroHealth Weight Loss Surgery Program

MetroHealth Weight Loss Surgery Program

4.0 (2 reviews) Weight loss service
2500 Metrohealth Dr, Cleveland, OH 44109
(216) 778-7433
“I initially had a very positive experience with this clinic-after all, I have lost 75 pounds through following their diet. I absolutely loved Dr. Catherine Lyo…” — Barbara Padgett
#6
LYV The Wellness Space

LYV The Wellness Space

4.8 Specialized clinic Today: 8 AM–6 PM
1870 W 25th St, Cleveland, OH 44113
(216) 242-1641
“Had a great experience with the team at LyV this morning. I really enjoyed their intake process, tour and explanation of all services. We are so lucky to have …” — Aimee Polgar
#7
Vitality Lounge Med Spa

Vitality Lounge Med Spa

5.0 Weight loss service Today: 10 AM–6 PM
2220 Superior Viaduct, Cleveland, OH 44113
(216) 202-4770
“ok experience” — Ms. B
#8
Sculpt Fitness Cleveland

Sculpt Fitness Cleveland

5.0 Weight loss service Today: 6 AM–7:30 PM
Bottom Level, 1468 W 9th St, Cleveland, OH 44113
(216) 200-4810
“Sculpt is my new personality. I lovvvvvvvve this gym, I love Ellie, I love the variety of the workouts & my body feels completely amazing after we train. Obses…” — Sophie Shiloh
#9
Cleveland Clinic Bariatric

Cleveland Clinic Bariatric

2.8 Surgical center Today: 9 AM–5 PM
9500 Euclid Ave, Cleveland, OH 44195
(216) 445-2224
“I called to get my process started and I can't get a call back to save my life. I will be going over to University hospital at this point. If calling people ba…” — darryl bush
#10
NuIQ Wellness Lounge & Med Spa

NuIQ Wellness Lounge & Med Spa

5.0 Weight loss service Today: 9 AM–7 PM
5450 Detroit Ave, Cleveland, OH 44102
(216) 377-1778
“The staff is friendly and knowledgeable, and the treatments are top-notch! Definitely recommend if you are looking for a high-quality med spa experience in the…” — Kaity Kline
#11
Options Medical Weight Loss Clinic

Options Medical Weight Loss Clinic

4.8 (37 reviews) Weight loss service Today: 8 AM–7 PM
13941 Cedar Rd, South Euclid, OH 44118
(216) 377-1220
“I couldn’t recommend this Clinic anymore than I already can I’ve went here with a struggling weight loss story I came in at 255lbs but didn’t start the program…” — Monae Johnson
#12
Shanail R. Berry, MD

Shanail R. Berry, MD

5.0 Weight loss service Today: 8 AM–5 PM
2500 Metrohealth Dr, Cleveland, OH 44109
(216) 778-7433
“Doctor Berry is caring very responsive and very professional. Her care and solutions have led to great improvements in my health in regard to weight and also …” — Tony Liotta

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Cleveland in a few days.

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What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Cleveland patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Cleveland

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Cleveland, Ohio

You can get weight loss shots in Cleveland at the local medical weight-loss clinics ranked on this page, or online through a licensed telehealth provider that ships semaglutide or tirzepatide to your home. Both require a prescription from a Ohio-licensed provider.

In clinical trials, semaglutide patients lost about 15% of body weight and tirzepatide patients up to 22.5% over roughly 68–72 weeks on the highest dose. For a 200-pound person that is roughly 30–45 pounds. Results in Cleveland vary with diet, activity and starting weight.

GLP-1 medications are given as a once-weekly subcutaneous injection with a small, thin needle — either a prefilled pen or a vial and syringe. They slow gastric emptying, reduce appetite and signal fullness to the brain. Most Cleveland patients self-inject at home after a quick demonstration; all supplies are included.

Most Cleveland patients complete the online assessment and get provider approval within 24 hours. Medication ships in 2–3 days, so you can start your first dose within about 3–4 days. The whole process is online with licensed Ohio providers.

Coverage varies widely by plan in Ohio. Many commercial plans cover Mounjaro for diabetes and Wegovy/Zepbound for weight management with prior authorization. Medicare Part D may cover diabetes indications but generally not weight-loss use. A Cleveland provider can verify benefits and file prior authorization.

Medication ships directly to your home in Cleveland, Ohio in temperature-controlled, discreet packaging, typically within 2–3 business days of approval. Needles, syringes and alcohol wipes are included.

GLP-1 weight loss explained

Weight loss clinics near Cleveland

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Weight Loss Shots and GLP-1 clinics across Ohio

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Ready to start GLP-1 treatment in Cleveland?

Compare local clinics above, or get a prescription online from a licensed Ohio provider and have it delivered.

Find Weight Loss Shots
Find Weight Loss Shots