12 clinics in Columbus, OH
4.5/5 Google rating

Weight Loss Shots in Columbus, Ohio

In Columbus, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Ohio-licensed clinician, who confirms your eligibility and sets your weekly dose.

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Weight loss shots in Columbus, OH
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Where to get weight loss shots in Columbus

In Columbus, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a Ohio-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near Columbus

The clinics listed for Columbus offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Columbus within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Columbus

In Columbus, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your Ohio plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Columbus

Three simple steps, online or at a local clinic

1
Online eligibility check

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed Ohio provider confirms if a GLP-1 is right for you.

2
Clinic or online provider

Get your prescription

Choose a local Columbus clinic for in-person care, or an online provider who ships medication to your door.

3
Start weekly treatment

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Am I eligible for a GLP-1 in Columbus?

Most providers require a BMI of 30 or higher, or 27+ with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. Check your BMI in seconds:

  • BMI 30+ — generally eligible
  • BMI 27–29 with a comorbidity — often eligible
  • A licensed Ohio provider confirms in minutes
Quick BMI check

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Columbus patients

ShotMoleculeApproved forFrequencyTypical price
Ozempic Semaglutide Type 2 diabetes (off-label weight loss) Once weekly $950–$1,350/mo
Wegovy Semaglutide Chronic weight management Once weekly $1,300–$1,400/mo
Mounjaro Tirzepatide Type 2 diabetes (off-label weight loss) Once weekly $1,000–$1,200/mo
Zepbound Tirzepatide Chronic weight management Once weekly $1,000–$1,060/mo
Compounded Semaglutide / Tirzepatide Cash-pay telehealth option Once weekly $199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Columbus

Compare by speed, price and how you prefer to be seen

Local clinics & med spas

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care
See clinics below
Retail pharmacy + insurance

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage
Learn more

Weight loss clinics in Columbus, OH

12 clinics offering GLP-1 treatment near Columbus, ranked by Google rating

#1
Ohio State Comprehensive Weight Management Martha Morehouse Outpatient Care

Ohio State Comprehensive Weight Management Martha Morehouse Outpatient Care

Weight loss service Today: 8 AM–4:30 PM
2050 Kenny Rd Fl Suite 1473, Columbus, OH 43221
(614) 366-6675
#2
Integrative Wellness Center

Integrative Wellness Center

4.8 Weight loss service Today: 9 AM–5 PM
1243 E Broad St, Columbus, OH 43205
(614) 321-7856
“I've been apart of this family for almost a year now and it's been an amazing part of my recovery as well as my life. Mr Ken as always been kind and listen to …” — Roy Richards
#3
Fitness Resources -Personalized Training Systems

Fitness Resources -Personalized Training Systems

5.0 Weight loss service Today: Open 24 hours
1002 N 4th St, Columbus, OH 43201
(614) 286-7883
“My experience working with Mark has been fantastic. He’s friendly, professional and the studio is clean and well equipped. The work outs are challenging and Ma…” — Tom Lasley
#4
Ohio State Martha Morehouse Outpatient Care

Ohio State Martha Morehouse Outpatient Care

4.1 Medical clinic Today: 8 AM–5 PM
2050 Kenny Rd Pavilion 2nd Floor Suite 2400, Columbus, OH 43221
(614) 293-8054
“I highly recommend Dr. Wegman and her staff!” — Susan Goeschl
#5
Ohio State Bariatric Surgery Martha Morehouse Outpatient Care

Ohio State Bariatric Surgery Martha Morehouse Outpatient Care

4.7 Surgical center Today: 8 AM–4:30 PM
2050 Kenny Rd #1222, Columbus, OH 43221
(614) 366-6675
“Dr Rhodes is very knowledgeable and caring. She has kept me going on my journey to a more healthy and happy me!” — Dawn Thornton
#6

OSU Bariatric Surgery & Other

2.9 (13 reviews) Weight loss service
2050 Kenny Rd, Columbus, OH 43221
(614) 293-5123
“Eva the psychologist is the worst she got my surgery denied and im very upset. She isn't professional at all. U don't answer things to her satisfaction then sh…” — valerie Chapman
#7
Options Medical Weight Loss Clinic

Options Medical Weight Loss Clinic

4.7 (377 reviews) Weight loss service Today: 8 AM–7 PM
959 E Johnstown Rd, Gahanna, OH 43230
(614) 636-4609
“Save your time and money. I had an appointment two weeks back, believing I was seeing a doctor. I saw an office manager who then scheduled a video appointment …” — Misty Sorrell
#8
Ohio Men's Health

Ohio Men's Health

5.0 (371 reviews) Medical clinic Today: 7 AM–7 PM
85 E Gay St #200, Columbus, OH 43215
(330) 662-1030
“Dr Troy is amazing and makes sure you are completely comfortable with the process before you begin. He does his due diligence to make sure you are doing what i…” — Brandon Mercer
#9
Buckeye Weight Loss

Buckeye Weight Loss

4.5 (41 reviews) Weight loss service Today: 9 AM–8 PM
3518 Riverside Dr, Upper Arlington, OH 43221
(614) 725-0443
“Something has gone wrong- set up an appointment online and paid $35 to hold the spot at the Riverside location. Needed to change appt and phone rings and r…” — Becky Rehbeck
#10
Hydrate Me Medspa - Grandview

Hydrate Me Medspa - Grandview

4.8 Medical spa Today: 10 AM–6 PM
955 W 5th Ave, Columbus, OH 43212
(614) 297-7565
“I came in for an IV the week of my wedding, and the whole staff was amazing! I’m not great with needles, but Sidney was so caring, patient, and attentive, whic…” — Reagan Morman
#11
OhioHealth Weight Management

OhioHealth Weight Management

3.8 Nutritionist
3773 Olentangy River Rd, Columbus, OH 43214
(614) 566-2700
“i’m too mentally ill to be treated here. i was told i have an eating disorder (which most fat people do) then i was told that was the root cause of my problems…” — Hailee Calevro
#12
Options Medical Weight Loss Clinic

Options Medical Weight Loss Clinic

4.8 (63 reviews) Weight loss service Today: 8 AM–7 PM
4084 Gantz Rd, Grove City, OH 43123
(614) 318-4100
“Staff is great, and I'm losing weight just as designed. Great experience so far. Down 8 lbs of just fat in the first month alone and feeling good.<br>Update...…” — Jason Pugh

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Columbus in a few days.

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What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Columbus patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Columbus

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Columbus, Ohio

Semaglutide (Ozempic, Wegovy) targets one receptor and averages ~15% weight loss; tirzepatide (Mounjaro, Zepbound) targets two receptors and reaches up to ~22.5%. Tirzepatide is generally more effective but costs more. A Columbus provider helps you choose.

Most people notice reduced appetite within the first week or two, with meaningful weight loss over months. Trials showed ~5–10% loss by three months. Providers in Columbus start you at a low dose and increase gradually, so results build steadily rather than overnight.

To qualify for a GLP-1 in Columbus you typically need a BMI of 30 or higher, or 27 or higher with a weight-related condition such as hypertension, type 2 diabetes, or high cholesterol. A free online assessment with a licensed Ohio provider confirms your eligibility in minutes.

You have three routes in Columbus: a licensed telehealth provider who ships medication to your door, a local weight-loss clinic or med spa for in-person care, or a retail pharmacy with a prescription (cheapest if insurance covers it). The clinics listed on this page are real, ranked by Google rating, with reviews and hours.

GLP-1 medications are given as a once-weekly subcutaneous injection with a small, thin needle — either a prefilled pen or a vial and syringe. They slow gastric emptying, reduce appetite and signal fullness to the brain. Most Columbus patients self-inject at home after a quick demonstration; all supplies are included.

No. Columbus telehealth providers offer cash-pay compounded options with a free online consultation, and HSA/FSA cards are accepted. Insurance is applied when available to further reduce your cost.

GLP-1 weight loss explained

Weight loss clinics near Columbus

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Weight Loss Shots and GLP-1 clinics across Ohio

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Ready to start GLP-1 treatment in Columbus?

Compare local clinics above, or get a prescription online from a licensed Ohio provider and have it delivered.

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Find Weight Loss Shots