12 clinics in Charleston, SC
4.5/5 Google rating

Weight Loss Shots in Charleston, South Carolina

In Charleston, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a South Carolina-licensed clinician, who confirms your eligibility and sets your weekly dose.

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Weight loss shots in Charleston, SC
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Where to get weight loss shots in Charleston

In Charleston, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a South Carolina-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near Charleston

The clinics listed for Charleston offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Charleston within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Charleston

In Charleston, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your South Carolina plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Charleston

Three simple steps, online or at a local clinic

1
Online eligibility check

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed South Carolina provider confirms if a GLP-1 is right for you.

2
Clinic or online provider

Get your prescription

Choose a local Charleston clinic for in-person care, or an online provider who ships medication to your door.

3
Start weekly treatment

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Am I eligible for a GLP-1 in Charleston?

Most providers require a BMI of 30 or higher, or 27+ with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. Check your BMI in seconds:

  • BMI 30+ — generally eligible
  • BMI 27–29 with a comorbidity — often eligible
  • A licensed South Carolina provider confirms in minutes
Quick BMI check

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Charleston patients

ShotMoleculeApproved forFrequencyTypical price
Ozempic Semaglutide Type 2 diabetes (off-label weight loss) Once weekly $950–$1,350/mo
Wegovy Semaglutide Chronic weight management Once weekly $1,300–$1,400/mo
Mounjaro Tirzepatide Type 2 diabetes (off-label weight loss) Once weekly $1,000–$1,200/mo
Zepbound Tirzepatide Chronic weight management Once weekly $1,000–$1,060/mo
Compounded Semaglutide / Tirzepatide Cash-pay telehealth option Once weekly $199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Charleston

Compare by speed, price and how you prefer to be seen

Local clinics & med spas

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care
See clinics below
Retail pharmacy + insurance

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage
Learn more

Weight loss clinics in Charleston, SC

12 clinics offering GLP-1 treatment near Charleston, ranked by Google rating

#1
West Ashley Wellness and Rehab

West Ashley Wellness and Rehab

4.9 Chiropractor Today: 10 AM–5:30 PM
2 Carriage Ln, Charleston, SC 29407
(843) 571-3100
“The staff and Dr Luckie are absolutely fantastic! They pay attention to details and always make me feel like family!!” — Herbert Drayton Jr.
#2
Metabolic Medical Centers

Metabolic Medical Centers

5.0 (46 reviews) Weight loss service Today: 8 AM–5 PM
821 Orleans Rd Unit 104, Charleston, SC 29407
(843) 573-9910
“Always so nice and friendly. I have been coming here a year and they are excellent.” — Tara GERARDI
#3
Physician's Plan

Physician's Plan

5.0 (246 reviews) Weight loss service Today: 8 AM–6 PM
12-A Farmfield Ave, Charleston, SC 29407
(843) 769-5510
“Friendly staff… they focus on your positives and encourage with recipes. They are my choice for weight loss guidance. I’ve tried 2 other places in the past b…” — Kathleen Miller
#4
Slim Rx Medical Weight Loss

Slim Rx Medical Weight Loss

4.9 (217 reviews) Weight loss service Today: 8:30 AM–5 PM
180 Wingo Way #106, Mt Pleasant, SC 29464
(843) 400-4060
“I can't say enough about how wonderful Chris & the staff are at Slim Rx. I'm less than 3 months in but have lost 25 pounds - more than I've ever been able to l…” — Saneva Maxine
#5
Lowcountry Wellness Center

Lowcountry Wellness Center

4.8 Medical clinic Today: 9 AM–5 PM
1565 Sam Rittenberg Blvd Ste 201, Charleston, SC 29407
(843) 793-1353
““Excellent service and caring staff! Lowcountry Wellness Center truly goes above and beyond for their clients.”” — Tamatha
#6
Metabolic Mentorship - Charleston Weight Loss

Metabolic Mentorship - Charleston Weight Loss

1.0 Medical Center
761 St Andrews Blvd, Charleston, SC 29407
(843) 873-6004
“I have tried to use this to schedule a call but always get no times available. Very frustrating!!!” — Laura Reinhardt
#7
Lowcountry Male Clinic - Mt. Pleasant, SC - TRT and Weight Loss Services

Lowcountry Male Clinic - Mt. Pleasant, SC - TRT and Weight Loss Services

4.6 (86 reviews) Weight loss service Today: 8:30 AM–5 PM
615 Johnnie Dodds Blvd Ste 102, Mt Pleasant, SC 29464
(843) 936-6451
“Absolutely recommend. Everyone is always very friendly! Shellie is the best!!” — jay g.
#8
The Drip Lounge

The Drip Lounge

5.0 Weight loss service Today: 9 AM–4 PM
564 King St, Charleston, SC 29403
(843) 990-4700
“Amazing place with wonderful employees!!” — Kristen Schafer
#9
Connection Health Center

Connection Health Center

5.0 Chiropractor Today: 8 AM–6 PM
708 King St #2, Charleston, SC 29403
(843) 410-9242
“I had a nagging hand injury that I was convinced was going to ruin my golf trip to Bandon Dunes. Dr. Grace recommended dry needling with Dr. Lissette and I’m g…” — Brett Cunningham
#10
MUSC Health Bariatric Surgery at Ashley River Tower

MUSC Health Bariatric Surgery at Ashley River Tower

4.4 (5 reviews) Weight loss service Today: 8 AM–5 PM
25 Courtenay Dr, Charleston, SC 29425
(843) 792-3046
“Dr Byrnes and his staff are absolutely 💯 awesome. In about 5 to 6 weeks I was seen by his staff and himself and this morning I'm waking up in the hospital hop…” — DON YARBOROUGH
#11
Roper St. Francis Physician Partners Bariatric Surgery

Roper St. Francis Physician Partners Bariatric Surgery

4.4 (33 reviews) Weight loss service Today: 8 AM–4 PM
2093 Henry Tecklenburg Dr #202E, Charleston, SC 29414
(843) 958-2590
“Quick personable and very informative.” — Craig Hazelnis
#12
The Spa West Ashley

The Spa West Ashley

4.8 Medical spa Today: 10 AM–6 PM
2 Carriage Ln 2nd floor, Charleston, SC 29407
(843) 225-9810
“Wonderful service! Brianna is exceptionally friendly and knowledgeable. She makes you feel instantly comfortable with the Cool Sculpting process.” — Cindy Allestad-Lyle

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Charleston in a few days.

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What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Charleston patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Charleston

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Charleston, South Carolina

GLP-1 pricing in Charleston depends on the option. Brand-name Ozempic, Wegovy, Mounjaro and Zepbound run about $950–$1,400/month without insurance, though manufacturer savings cards can cut that sharply for eligible South Carolina patients. Compounded semaglutide or tirzepatide via telehealth is the most affordable cash-pay route, with all-inclusive plans from around $199/month.

Compounded GLP-1s are prepared by 503A/503B pharmacies regulated by state boards and the FDA, with purity independently tested. They contain the same active ingredient as the brand-name drugs. Your Charleston provider monitors your progress and adjusts your protocol as needed.

Both are semaglutide from Novo Nordisk. Ozempic is FDA-approved for type 2 diabetes (often used off-label for weight loss), while Wegovy is approved specifically for chronic weight management at a higher dose. Same molecule, different indication and dosing.

Standard criteria: BMI 30 or higher, or 27 or higher with a weight-related comorbidity such as hypertension, type 2 diabetes, dyslipidemia or sleep apnea. Charleston providers follow FDA-guided criteria; a free assessment confirms eligibility in minutes.

Yes — licensed telehealth providers handle everything online in Charleston, from assessment to prescription. A South Carolina-licensed provider reviews your history, runs a virtual consult and ships medication to your address. Local clinics on this page are the in-person alternative.

Brand-name GLP-1s come as prefilled pens (pre-measured, very easy to use). Compounded medication often ships as a vial with syringes, which costs less and lets the provider fine-tune the dose. Both deliver the same weekly subcutaneous injection; your Charleston provider will recommend what fits you.

GLP-1 weight loss explained

Weight loss clinics near Charleston

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Weight Loss Shots and GLP-1 clinics across South Carolina

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Ready to start GLP-1 treatment in Charleston?

Compare local clinics above, or get a prescription online from a licensed South Carolina provider and have it delivered.

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