9 clinics in Monroe, SD

4.7/5 Google rating

Weight Loss Shots in Monroe, South Dakota

In Monroe, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a South Dakota-licensed clinician, who confirms your eligibility and sets your weekly dose.

Find Weight Loss Shots

Local clinics + online Licensed providers Delivery in 2–3 days From $199/mo

Where to get weight loss shots in Monroe

Semaglutide and tirzepatide shots near Monroe

The clinics listed for Monroe offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Monroe within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Monroe

In Monroe, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your South Dakota plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Monroe

Three simple steps, online or at a local clinic

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed South Dakota provider confirms if a GLP-1 is right for you.

Get your prescription

Choose a local Monroe clinic for in-person care, or an online provider who ships medication to your door.

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Monroe patients

Shot	Molecule	Approved for	Frequency	Typical price
Ozempic	Semaglutide	Type 2 diabetes (off-label weight loss)	Once weekly	$950–$1,350/mo
Wegovy	Semaglutide	Chronic weight management	Once weekly	$1,300–$1,400/mo
Mounjaro	Tirzepatide	Type 2 diabetes (off-label weight loss)	Once weekly	$1,000–$1,200/mo
Zepbound	Tirzepatide	Chronic weight management	Once weekly	$1,000–$1,060/mo
Compounded	Semaglutide / Tirzepatide	Cash-pay telehealth option	Once weekly	$199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Monroe

Compare by speed, price and how you prefer to be seen

Telehealth delivery

From $199/mo (compounded)

Online consultation with a licensed provider, medication shipped to your door. Fastest cash-pay route, no insurance needed.

Best for speed & convenience

Find Weight Loss Shots

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care

See clinics below

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage

Learn more

Weight loss clinics in Monroe, SD

9 clinics offering GLP-1 treatment near Monroe, ranked by Google rating

Sioux Falls Secret for Weight Loss

4.9 (35 reviews) Weight loss service Today: 8–11 AM

600 W 37th St Suite A, Sioux Falls, SD 57105

(605) 274-6262

“You guys are very friendly, encouraging, and flexible. I have learned a lot and am eager to continue losing weight at this pace. I feel good every day and I …” — Sue Wagner

Yevo Semaglutide & Weight Loss of Sioux Falls

Weight loss service Today: Open 24 hours

2841 E Old Orchard Trail, Sioux Falls, SD 57103

(951) 507-1118

Sanford Weight Management Center

5.0 Nutritionist Today: 7 AM–5 PM

3401 W 49th St, Sioux Falls, SD 57106

(605) 328-8670

“Dr. Jennifer Schriever and Lindsay Stern are some of the best people I’ve ever witnessed in healthcare… And this is come coming from someone who spent almost a…” — Jess Schnyders

Avera Comprehensive Weight Management — 41st & Holbrook

2.7 (10 reviews) Weight loss service Today: 7:30 AM–1 PM

6000 W 41st St Ste 100, Sioux Falls, SD 57106

(605) 504-0400

“The late, missed appointment policy is outrageous. Receptionists are extremely rude and unprofessional. If I could give zero stars I would.” — Samantha Kastengren

Encompass Wellness & Aesthetics

4.9 Weight loss service Today: 8 AM–6 PM

4301 W 57th St #160, Sioux Falls, SD 57108

(605) 740-0414

“Love this place! Everyone is so welcoming and kind! 10/10 recommend” — Maycee Guyer

A Weigh of Life

5.0 (1 reviews) Weight loss service Today: Closed

610 W 23rd St #10, Yankton, SD 57078

(605) 464-9624

Profile Plan - Personalized Weight Loss Plans (Virtual Location)

5.0 (101 reviews) Weight loss service

922 22nd Ave S, Brookings, SD 57006

(605) 705-4219

“I would have recommended this company but after being loyal for three years they have definitely just pushed out their loyal customers. Discontinued products a…” — Melisa Yager

Vibrance Medical, PLLC

5.0 (16 reviews) Weight loss service Today: Closed

101 Tower Rd #103, Dakota Dunes, SD 57049

(605) 534-4043

“The staff at Vibrance Medical are very knowledgeable, pleasant, friendly and helpful. I have a positive experience with every visit. Highly recommend Vibranc…” — Sara Magstadt

Profile Plan - Personalized Weight Loss Plans (Virtual Location)

4.9 (161 reviews) Weight loss service

1900 S Minnesota Ave, Sioux Falls, SD 57105

(605) 370-6322

“Profile by Sanford (now Profile Plan) is an excellent health and wellness program, and their partnership with MNSEI makes it even more accessible! By offering …” — State Employees Inc (State Employees Inc)

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Monroe in a few days.

Find Weight Loss Shots

What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Monroe patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Monroe

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Monroe, South Dakota

You can get weight loss shots in Monroe at the local medical weight-loss clinics ranked on this page, or online through a licensed telehealth provider that ships semaglutide or tirzepatide to your home. Both require a prescription from a South Dakota-licensed provider.

GLP-1 pricing in Monroe depends on the option. Brand-name Ozempic, Wegovy, Mounjaro and Zepbound run about $950–$1,400/month without insurance, though manufacturer savings cards can cut that sharply for eligible South Dakota patients. Compounded semaglutide or tirzepatide via telehealth is the most affordable cash-pay route, with all-inclusive plans from around $199/month.

Clinical trials show tirzepatide (Mounjaro/Zepbound) produces greater average weight loss (up to ~22.5% of body weight) than semaglutide (Ozempic/Wegovy, ~15–17%). Tirzepatide activates two receptors (GLP-1 and GIP) versus one for semaglutide. Both are highly effective; your Monroe provider helps choose based on your history and goals.

In clinical trials, semaglutide patients lost about 15% of body weight and tirzepatide patients up to 22.5% over roughly 68–72 weeks on the highest dose. For a 200-pound person that is roughly 30–45 pounds. Results in Monroe vary with diet, activity and starting weight.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks as the dose increases. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns. Your Monroe provider starts you low and monitors progress.

Standard criteria: BMI 30 or higher, or 27 or higher with a weight-related comorbidity such as hypertension, type 2 diabetes, dyslipidemia or sleep apnea. Monroe providers follow FDA-guided criteria; a free assessment confirms eligibility in minutes.

Weight Loss Shots in Monroe, South Dakota

Where to get weight loss shots in Monroe

Semaglutide and tirzepatide shots near Monroe

What weight loss shots cost in Monroe