12 clinics in Rapid City, SD
4.9/5 Google rating

Weight Loss Shots in Rapid City, South Dakota

In Rapid City, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a South Dakota-licensed clinician, who confirms your eligibility and sets your weekly dose.

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Weight loss shots in Rapid City, SD
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Where to get weight loss shots in Rapid City

In Rapid City, weight loss shots are available at local medical weight-loss clinics and med spas — ranked below by Google rating with reviews and hours — or online through licensed telehealth providers who ship semaglutide and tirzepatide to your door. Both routes require a prescription from a South Dakota-licensed clinician, who confirms your eligibility and sets your weekly dose.

Semaglutide and tirzepatide shots near Rapid City

The clinics listed for Rapid City offer once-weekly semaglutide or tirzepatide injections under physician supervision, often with in-office dosing and follow-up. If you prefer to start from home, a telehealth provider can prescribe compounded shots and deliver them to Rapid City within a few days. Compare local clinics and online delivery to find what fits your schedule and budget.

What weight loss shots cost in Rapid City

In Rapid City, brand-name shots (Wegovy, Zepbound) cost roughly $1,000–$1,400/month without insurance, while compounded semaglutide or tirzepatide through telehealth starts around $199/month all-inclusive. If your South Dakota plan covers a GLP-1, your copay may drop to $25–$50. Many local clinics offer monthly membership pricing — check the listings below and compare against online options.

How to get weight loss shots in Rapid City

Three simple steps, online or at a local clinic

1
Online eligibility check

Check your eligibility

Complete a quick health assessment (BMI 27+). A licensed South Dakota provider confirms if a GLP-1 is right for you.

2
Clinic or online provider

Get your prescription

Choose a local Rapid City clinic for in-person care, or an online provider who ships medication to your door.

3
Start weekly treatment

Start weekly treatment

Begin your once-weekly injection at a low dose, with provider follow-up to adjust as you progress.

Am I eligible for a GLP-1 in Rapid City?

Most providers require a BMI of 30 or higher, or 27+ with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. Check your BMI in seconds:

  • BMI 30+ — generally eligible
  • BMI 27–29 with a comorbidity — often eligible
  • A licensed South Dakota provider confirms in minutes
Quick BMI check

Semaglutide vs. tirzepatide & the GLP-1 options

Brand-name and compounded options available to Rapid City patients

ShotMoleculeApproved forFrequencyTypical price
Ozempic Semaglutide Type 2 diabetes (off-label weight loss) Once weekly $950–$1,350/mo
Wegovy Semaglutide Chronic weight management Once weekly $1,300–$1,400/mo
Mounjaro Tirzepatide Type 2 diabetes (off-label weight loss) Once weekly $1,000–$1,200/mo
Zepbound Tirzepatide Chronic weight management Once weekly $1,000–$1,060/mo
Compounded Semaglutide / Tirzepatide Cash-pay telehealth option Once weekly $199–$499/mo

Prices are typical U.S. cash-pay ranges without insurance; manufacturer savings cards and coverage can lower brand-name costs significantly.

Three ways to get weight loss shots in Rapid City

Compare by speed, price and how you prefer to be seen

Local clinics & med spas

Local clinics & med spas

Varies by clinic

In-person medical weight loss clinics near you — physician oversight, injections on site, personalized follow-up.

Best for in-person care
See clinics below
Retail pharmacy + insurance

Retail pharmacy + insurance

Copay $25–$50 if covered

Brand-name Ozempic/Wegovy/Mounjaro/Zepbound with a prescription, filled at your pharmacy. Cheapest if covered.

Best if you have coverage
Learn more

Weight loss clinics in Rapid City, SD

12 clinics offering GLP-1 treatment near Rapid City, ranked by Google rating

#1
Monument Health Weight Management - Rapid City

Monument Health Weight Management - Rapid City

Medical clinic Today: Closed
1136 Jackson Blvd, Rapid City, SD 57702
(605) 755-5700
#2
Monument Health Lifestyle Medicine

Monument Health Lifestyle Medicine

4.9 Weight loss service Today: Closed
640 Flormann St, Rapid City, SD 57701
(605) 755-1375
“Such friendly, professional and caring people. From check in to check out I was treated with respect and kindness. My visit with Dr. Fuller was not rushed in…” — Iva Carter
#3
Gameday Men's Health Rapid City, SD

Gameday Men's Health Rapid City, SD

4.9 (120 reviews) Weight loss service Today: Closed
1301 W Omaha St Ste 224, Rapid City, SD 57701
(605) 204-6757
“These folks are great! Highly reccomend!” — Kinzie Foods
#4
Peak Wellness - Personalized nutrition, activity and lifestyle coaching

Peak Wellness - Personalized nutrition, activity and lifestyle coaching

4.9 (147 reviews) Weight loss service
2050 W Main St Ste 1, Rapid City, SD 57702
“Peak Wellness has a wonderful program in place - from helpful, encouraging coaches, yummy food products, activities and a supportive app for tracking progress…” — Vonda Jones
#5

Feel Ideal Rapid City- Weight Loss Clinic

Weight loss service Today: Closed
E, 1764 Centre St, Rapid City, SD 57703
(605) 484-7811
#6
MOSAIC Medicine

MOSAIC Medicine

5.0 Medical spa Today: Closed
2800 Jackson Blvd Ste 2, Rapid City, SD 57702
(605) 503-7020
“I love all my office visits. I have learned so much about myself and all my needs are taken seriously. Thank you!” — Chilatah Hozhoon
#7

Reset Weight

5.0 (2 reviews) Weight loss service
1624 E Saint Patrick St, Rapid City, SD 57703
(605) 391-8697
“Cheryl is a wonderful business woman who is committed to helping others with a healthy lifestyle. if you are looking to make a big change, give her a call!” — Little Nest
#8
Remedy 605

Remedy 605

4.9 Medical spa Today: Closed
731 St Joseph St Ste 230, Rapid City, SD 57701
(605) 608-4004
“I went in for a weight loss consultation and a skin consultation. From the beginning, they made me feel comfortable and way less anxious. I wasn’t sure what to…” — Beka L.
#9
Health Concepts

Health Concepts

4.8 Medical clinic Today: Closed
5410 Sheridan Lake Rd, Rapid City, SD 57702
(605) 348-4141
“Great staff” — Joseph Reiser
#10
Well Beyond Functional Medicine

Well Beyond Functional Medicine

4.8 Medical clinic Today: Closed
3808 Sheridan Lake Rd Ste 101, Rapid City, SD 57702
(605) 219-9525
“Words cannot describe how grateful I am for Cathy!!!! I have had gut problems for many years and nobody was able to give me a straight answer. I saw doctors an…” — Justin Streeter
#11
WW Studio @ Rushmore Jukite Ju-Jitsu Rapid City

WW Studio @ Rushmore Jukite Ju-Jitsu Rapid City

Weight loss service Today: Closed
311 E Saint Patrick St, Rapid City, SD 57701
(800) 651-6000
#12
Monument Health General Surgery and Bariatrics

Monument Health General Surgery and Bariatrics

4.9 Surgeon Today: Closed
353 Fairmont Blvd, Rapid City, SD 57701
(605) 755-5700
“Dr. Larson and his staff are hands down the best! Everyone from the front desk staff to the Ca's/Ma's and nurses are so kind. Dr. Larson really listens!” — Alicia

Prefer to start from home? A licensed provider can prescribe and ship your GLP-1 to Rapid City in a few days.

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What to expect: dosing & side effects

GLP-1 medications are given as a once-weekly subcutaneous injection, starting at a low dose that your provider increases gradually over several weeks to limit side effects. Most Rapid City patients self-inject at home after a short demonstration.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns; GLP-1s should not be used by people with a personal or family history of medullary thyroid carcinoma or MEN 2. Your provider reviews your full history before prescribing.

Ways to save in Rapid City

Coverage and cash-pay options

Insurance Coverage

Many commercial plans cover GLP-1 therapy for eligible patients. Your provider can submit prior authorization for brand-name options.

Copay as low as $25–$50/month with insurance

HSA / FSA Eligible

GLP-1 medication prescribed by a licensed provider is an eligible HSA/FSA expense.

Pay with pre-tax dollars, saving 20–35%

Manufacturer Savings

Novo Nordisk and Eli Lilly offer savings cards for commercially insured patients who meet eligibility requirements.

Save up to $500+/month on eligible brands

Cash-Pay Compounded

Compounded semaglutide/tirzepatide via telehealth offers the lowest cash-pay entry point with no insurance.

All-inclusive plans from $199/month

Frequently asked questions

GLP-1 treatment in Rapid City, South Dakota

You can get weight loss shots in Rapid City at the local medical weight-loss clinics ranked on this page, or online through a licensed telehealth provider that ships semaglutide or tirzepatide to your home. Both require a prescription from a South Dakota-licensed provider.

Semaglutide (Ozempic, Wegovy) targets one receptor and averages ~15% weight loss; tirzepatide (Mounjaro, Zepbound) targets two receptors and reaches up to ~22.5%. Tirzepatide is generally more effective but costs more. A Rapid City provider helps you choose.

Most people notice reduced appetite within the first week or two, with meaningful weight loss over months. Trials showed ~5–10% loss by three months. Providers in Rapid City start you at a low dose and increase gradually, so results build steadily rather than overnight.

You have three routes in Rapid City: a licensed telehealth provider who ships medication to your door, a local weight-loss clinic or med spa for in-person care, or a retail pharmacy with a prescription (cheapest if insurance covers it). The clinics listed on this page are real, ranked by Google rating, with reviews and hours.

In clinical trials, semaglutide patients lost about 15% of body weight and tirzepatide patients up to 22.5% over roughly 68–72 weeks on the highest dose. For a 200-pound person that is roughly 30–45 pounds. Results in Rapid City vary with diet, activity and starting weight.

The most common side effects are nausea, diarrhea, constipation, decreased appetite and mild injection-site reactions — usually mild and fading over the first few weeks as the dose increases. Rare but serious risks include pancreatitis, gallbladder issues and thyroid concerns. Your Rapid City provider starts you low and monitors progress.

GLP-1 weight loss explained

Weight loss clinics near Rapid City

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Weight Loss Shots and GLP-1 clinics across South Dakota

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Ready to start GLP-1 treatment in Rapid City?

Compare local clinics above, or get a prescription online from a licensed South Dakota provider and have it delivered.

Find Weight Loss Shots
Find Weight Loss Shots